The manganese ore deposit of Praborna crops out in the Zermatt-Saas unit of the Western Alps, in the St. Marcel valley. It represents a Jurassic ophiolitic sedimentary cover subducted at high-pressure conditions during the Alpine orogeny. Major- and trace-element analyses of representative samples of the ore and the host metasediments were collected to geochemically characterise the deposit. Selected phases (piemontite, braunite, garnet, clinopyroxene, white mica and manganiandrosite) were investigated with ion and electron microprobes to link the mineral chemistry to the bulk-rock chemistry. Compared to shales, Praborna is enriched in Mn (up to 38.7 wt% Mn2O3) and in many trace elements (Sc, Co, Ni, Cu, Ge, As, Sr, Ag, Sb, Te, Ba, Tl, Pb and Bi). The bulk-rock REE pattern suggests 20 % hydrogenous and 80 % hydrothermal inputs in the proto-ore. Compared to the shale, the hanging-wall Mn-poor schists share with the Mn ore body the enrichment in Sc, Mn, Co, Sr and Te, suggesting a common enrichment process involving these elements. The REE pattern suggests a sedimentary origin for these schists, which were probably composed of clay mixed with components of volcanic origin.